What Is PRF?
Platelet-Rich Fibrin, or PRF, is a regenerative treatment that harnesses the healing power of your own biology to stimulate collagen production, achieve skin rejuvenation, and restore a more youthful appearance. Derived from a small sample of your own blood, PRF represents a significant advancement over traditional Platelet-Rich Plasma (PRP) therapy, offering greater biological activity and longer-lasting results.
To prepare PRF, a small amount of blood is drawn and placed in a centrifuge, where it is spun at a carefully calibrated, lower speed than conventional PRP processing. This technique preserves a richer concentration of platelets, growth factors, and white blood cells within a fibrin matrix, a natural scaffold that releases those regenerative factors gradually over time. The result is a treatment that is more bioactive, more sustained, and more effective at stimulating the body’s natural collagen and elastin production than earlier platelet-based therapies.
At UnionDerm, we offer two distinct PRF-based treatments: pure PRF injections and EZGel. Pure PRF is injected into targeted areas to improve skin texture, tone, and radiance, and to stimulate collagen renewal from within. EZGel is a next-generation PRF biofiller, created from your own blood and naturally occurring albumin protein, that is processed into a gel-like consistency and used to restore volume in areas of facial hollowing. Both treatments are entirely natural, biocompatible, and free of synthetic ingredients, with virtually no risk of allergic reaction.
What Is EZGel?
EZGel represents the leading edge of natural volumization. Using your own blood alongside albumin, a protein your body already produces, EZGel is processed into a smooth, injectable gel that behaves similarly to a traditional dermal filler but is composed entirely of your own biological material. It can be placed precisely into areas of volume loss to restore structure and softness, while simultaneously stimulating ongoing collagen regeneration in the surrounding tissue.
EZGel is particularly well-suited for restoring volume in the cheeks, temples, and under-eye area; softening deep folds and hollows; and addressing concerns in patients who prefer a fully natural alternative to synthetic fillers. Because it is derived entirely from your own body, EZGel integrates seamlessly with your existing tissue, and results continue to develop naturally as collagen remodeling progresses in the weeks following treatment.
Pure PRF and EZGel can also be used together in the same session, with each product addressing a different dimension of facial aging for a more complete, natural rejuvenation.
Why Choose UnionDerm for PRF?
At UnionDerm, PRF and EZGel treatments are performed exclusively by our board-certified dermatologists, physicians who have offered platelet-based therapies to patients for many years and bring a depth of experience to these treatments that is difficult to find elsewhere. Our team was administering PRP well before it became widely available, and that long clinical history with platelet-based therapy informs every aspect of how we approach PRF today.
Our dermatologists’ expertise extends across the full spectrum of injectable treatments, encompassing neurotoxins, hyaluronic acid, and biostimulatory fillers, and advanced regenerative therapies like PRF and EZGel. This breadth matters because no injectable treatment exists in isolation. Achieving truly natural, harmonious results requires understanding how different products and techniques interact across the face, and having the clinical judgment to design a plan that addresses each patient’s unique anatomy and goals. That level of nuanced, medically informed decision-making is something only a highly trained physician can provide.
At UnionDerm, PRF treatments are performed under the direction of our board-certified dermatologists, with every injection personally administered by your physician. Our doctors bring the training, experience, and aesthetic sensibility needed to deliver results that are both safe and genuinely transformative.
Who Is a Candidate for PRF?
PRF and EZGel are well-suited to a broad range of patients, particularly those seeking natural, biologically driven rejuvenation without synthetic ingredients or significant downtime. Ideal candidates present with concerns such as:
- Dullness, uneven tone, acne scars, or loss of skin radiance
- Fine lines and early textural changes
- Mild volume loss in the cheeks, temples, or under-eye area (dark circles)
- Overall skin quality concerns related to aging or sun damage
- A preference for natural, synthetic-free treatment options
- A desire to complement or enhance results from other injectable or energy-based treatments
Because PRF is derived entirely from your own blood, it is appropriate for virtually all skin types and tones and carries an exceptionally low risk of adverse reaction. A personalized consultation with one of our board-certified dermatologists will determine whether pure PRF, EZGel, or a combination approach is the most appropriate path to your facial rejuvenation goals.
What Can I Expect from PRF?
PRF and EZGel are minimally invasive treatments designed to be both effective and comfortable. A topical numbing cream is applied prior to treatment to maximize your ease, and most sessions are completed in 30 to 60 minutes from blood draw to final injection. There is no surgery, no synthetic material, and minimal downtime. Some patients experience mild redness, mild swelling, or bruising at the injection sites in the days following treatment, but these effects are typically brief and easily managed.
Because PRF works by stimulating your body’s own regenerative processes, results develop gradually rather than immediately. Many patients begin to notice improvements in skin quality, radiance, and texture within two to four weeks of their first session. Volume restoration with EZGel becomes more apparent as the product integrates and collagen remodeling continues, with results refining and deepening over two to three months. Most patients achieve their optimal outcome after a series of treatments, the precise number and spacing of which will be determined during your personalized consultation.
What Areas Can PRF Treat?
The versatility of PRF makes it one of the most comprehensive regenerative skin treatments available. Applications include:
- Face: improving overall skin quality, tone, and radiance across the full face
- Under-eye area: reducing hollowness and improving skin quality in the delicate periorbital region
- Cheeks and midface: restoring subtle volume and improving firmness with EZGel
- Temples: addressing hollowing and volume loss in the upper face
- Nasolabial folds and marionette lines: softening deeper folds with EZGel volumization
- Neck and decolletage: improving skin quality and texture in areas of sun damage or aging
- Scalp: stimulating hair follicle health and supporting hair restoration
Schedule a Consultation
Exceptional skin begins with a conversation. At UnionDerm, every new patient begins with a dedicated one-on-one consultation with a board-certified dermatologist. Your physician will assess your skin, listen closely to your concerns and aspirations, and design a customized treatment plan tailored precisely to you.
To schedule your consultation or an appointment for PRF or EZGel, please contact us today.
